October 15, 2008

Testosterone / Epitestosterone Ratio: How Is It Significant?

Testosterone is an anabolic steroid & a potent androgenic hormone which is produced naturally in the body by the male testes as well as female ovaries, although the proportional production in males and females vary significantly. It is known to be responsible for the development of male reproductive organs and secondary sexual characteristics & its use may lead to a significant increase in the muscle mass, mood changes, hair loss, deepened voice, acne and infertility although such effects are case, context & dose dependent.
A range of testosterone-like anabolic steroids have ceremoniously been abused to enhance muscle development, strength, and endurance in various sports & athletic competitions. Such sort of exogenous performance enhancement is considered to be a form of doping by most of the sports regulatory authorities.
Epitestosterone is an inactive stereoisomer of testosterone & has a different configuration at only one of several stereogenic centers. It is, thus, a chemically similar, natural steroid that is produced independently of testosterone through a different bio-synthetic pathway.
Usually, the amount of Testosterone (T) & Epitestosterone (E) are in similar proportions and their normal presence in urine has been found, on an average to be roughly equal to 1:1, although it varies on a […]

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